Gäller från och med: Autumn 2016
Beslutad av: Mats Ohlin
Datum för fastställande: 2016-11-30
Avdelning: Immunotechnology
Kurstyp: Ren forskarutbildningskurs
Undervisningsspråk: English
Mass spectrometry-based proteomics is showing great potential for giving new biological insight and for discovery of biomarkers. However, the utility of results from proteomics experiments is highly dependent on data analysis and experimental design. The aim of the course is to give the attendants insight into the different steps of data analysis associated with mass spectrometry-based quantitative proteomics experiments, to allow for selection of workflow and to perform basic data analysis.
Kunskap och förståelse
För godkänd kurs skall doktoranden
Färdighet och förmåga
För godkänd kurs skall doktoranden
Värderingsförmåga och förhållningssätt
För godkänd kurs skall doktoranden
In this post-graduate course, properties of data from quantitative mass spectrometry-based proteomics will be discussed, based on hands-on examples with practical data analysis. The course attendants will get an overview of existing solutions for analysis of proteomics data. Lectures in the course will cover 1) proteomics experimental planning, encompassing selection of workflow and sample selection, 2) raw data handling and analysis using informatic tools, including validation of peptide and protein identifications, 3) formatting of data for publication and deposition in public repositories, and 4) basic statistical analysis of results, and functional annotation. The exercises will encompass planning of experiments and evaluation of data from two different quantitative proteomics workflows, and discussion of significance and interpretation of the results.
Slides and articles will be distributed
Undervisningsformer: Föreläsningar, seminarier, övningar
Examinationsformer: Inlämningsuppgifter, seminarieföredrag av deltagarna.
Active participation in lectures, exercises and discussion seminar.
Betygsskala: Underkänd, godkänd
Examinator:
The course is given each autumn through the Postgraduate Courses in the Life Sciences (http://www.cmps.lu.se/life_sciences) if at least 6 students are accepted.
Kursansvariga: