Frontiers in Organic Synthesis
Fronter i organisk syntes

KAS020F, 7.5 högskolepoäng

Gäller från och med: Spring 2020
Beslutad av: Margareta Sandahl
Datum för fastställande: 2020-03-19

Allmänna uppgifter

Avdelning: Centre for Analysis and Synthesis (CAS)
Kurstyp: Ren forskarutbildningskurs
Undervisningsspråk: English

Syfte

The course aims to deepen and broaden the students knowledge of modern organic synthesis strategies and methods. The course will cover methods with respect to synthesis planning, retrosynthetic analysis, and the synthon approach with respect to functional group strategies and stereochemical strategies, as well as target structure and topology.

Mål

Kunskap och förståelse

För godkänd kurs skall doktoranden be able to describe different strategies for planning multi-step syntheses.

Färdighet och förmåga

För godkänd kurs skall doktoranden

• be able to apply selected synthesis planning strategies to reach comprehensive retro-synthetic analyses.
• be able to propose a viable synthetic plan based on modern chemical reactions and on a retro-synthetic analysis.

Värderingsförmåga och förhållningssätt

För godkänd kurs skall doktoranden

• be able to compare and evaluate merits of different retro-synthetic analyses towards a given target molecule.
• be able to compare and evaluate scope and limitations of alternative reagents chosen for transformations within a proposed organic synthesis sequence.

Kursinnehåll

Seminars on selected topics in advanced contemporary organic synthesis planning and retro-synthetic analysis. Each student will present an in-depth seminar on a topic within the course. Topics will be selected by the student with advise from course teachers. Part of the presentation assignment is feedback from peers and teachers.

Kurslitteratur

Nicolaou, K. C. & Chen, Jason S.: Classics in Total Synthesis III: Further Targets, Strategies, Methods. John Wiley & Sons, 2011. ISBN 9783527329571.
Classics in Total Synthesis III: Further Targets, Strategies, Methods. Selected original and review publications.

Kursens undervisningsformer

Undervisningsformer: Seminarier, litteraturkurs som självstudier

Kursens examination

Examinationsformer: Seminarieföredrag av deltagarna, övrigt. Active participation in seminars (passed/not passed). Active attendance on presentation assignments by other students and opposition on one presentation (passed/not passed) Presentation and discussion of an assignment (passed/not passed). Final examination with questions in connection with the presentations (passed/not passed).
Betygsskala: Underkänd, godkänd
Examinator: Professor Kenneth Wärnmark

Antagningsuppgifter

Förutsatta förkunskaper: KAS003F or equivalent
Minsta antal deltagare: 5

Kurstillfällesinformation

Startdatum: 2020-05-04
Slutdatum: 2020-10-31
Kursfart: Half time

Anmälningsinformation

Email to course coordinator

Kontaktinformation och övrigt

Kursansvariga:

• Ulf Nilsson <ulf.nilsson@chem.lu.se>
• Kenneth Wärnmark <kenneth.warnmark@chem.lu.se>