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Faculty of Engineering | Lund University

Details for the Course Syllabus for Course MAM035F valid from Autumn 2022

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General
Aim
  • The aim of Part 1 is to mediate knowledge of safe manufacturing and handling of engineered nanoparticles and of nanomaterials i.e. materials containing nanoparticles, in the perspective of human health and of environment. Aspects such as safety important particle characteristics, exposure and emission assessment, nanotoxicology, precautionary principle, safe-by-design, human-technology interaction, risk assessment, risk management, risk communication, life cycle analysis, legislation, and ethical aspects will be covered.
    The aim of Part 2 is to analyze, estimate, evaluate, judge, and communicate the human, societal, and environmental impacts of nanomaterials in one's own research, using terms, concepts, and risk management models obtained during Part 1.
Contents
  • Particle properties (size, shape, aspect-ratio, solubility, chemical composition), lung deposition and clearance, emissions, exposure, toxicity, risk management, human-technology interaction, biomarkers, engineering controls and personal protection, risk- and safety communication, food chain transport, life cycle analyses, ethical aspects, and legislation.
Knowledge and Understanding
  • For a passing grade the doctoral student must
  • be able to describe the concept of risk and how risk can be assessed in different stages (production, incorporation in consumer product, handling of product, end-of-life) of an engineered nanoparticle/nanomaterial
    be able to describe the concepts of precautionary principle and safe-by-design and how these concepts are employed in the nano technology research and development
    be able to connect different properties of an engineered nanoparticle/nanomaterial to human uptake through skin, lung and gastrointestinal tract
    describe the connections between handling of nanoparticle-containing products, nanoparticle emissions and environmental exposure
    describe basic mechanisms and health endpoints related to nanoparticle toxicity
    be able to use terms, concepts and risk models from Part 1 of the course when doing risk assessment and risk management for human, society, and environment of nanomaterials from one's own research
    identify risks in different stages (production, incorporation in consumer product, handling of product, end-of-life) of nanomaterials from one's own research
Competences and Skills
  • For a passing grade the doctoral student must
  • be able to carry out simple measurements of airborne nanoparticles and understand the results
    orally and in writing, with authority, be able to communicate safety aspects of nano technology research and development
    have compiled basic strategies, and motivations to these, to work towards implementing safe-by-design
    be able to collect relevant scientific literature and use it critically
    be able to apply and argument for precautionary measures of nanomaterials, and the handling of these materials, from one's own research
    orally and in writing, with authority, be able to present a risk assessment and risk management of one's own research
    suggest and argue for strategies towards implementing safe-by-design in one's own research
Judgement and Approach
  • For a passing grade the doctoral student must
  • be able to choose and motivate instruments to design an occupational exposure measurement
    demonstrate insight into the possibilities and limitations of research with a set of toxicological approaches (human, animal models, cell studies)
    be able to judge and interpret risk assessments related to production and handling of nanoparticles and nanomaterials.
    be able to identify knowledge gaps in nanosafety
    be able to discuss ethical and legal considerations related to nanosafety
    based on scientific literature be able to identify knowledge gaps in nanosafety related one's own research
    orally and in writing be able to discuss ethical and legal aspects related to nanomaterials from one's own research
    evaluate and judge the human, societal, and environmental impact of nanomaterials from one's own research
Types of Instruction
  • Lectures
  • Laboratory exercises
  • Project
  • Self-study literature review
Examination Formats
  • Written report
  • Written assignments
  • Seminars given by participants
  • Detailed description of the different examination formats. Part 1: 1) Approved individual home assignment before course start (summarize two scientific papers), and discussion of these in groups at start of course week 1; 2) 80% minimum participation to the lectures (1.5 weeks); 3) Approved group task to be done between course week 1 and course week 2, presented in writing and orally during course week 2; 4) Participation in laboratory exercise; 5) Approved final home assignment after course week 2 (hazard identification connected to doctoral student’s own research).
    Part 2: Approved report and oral presentation of health risk assessment (hazard, dose-response, exposure analysis), risk management and risk communication plan related to student's own research.
  • Failed, pass
Admission Requirements
  • The course is open for all PhD students within the fields of engineering, science, and medicine. The course is also open for representatives from industry and legislation, as well as master students with a documented interest in nanosafety, or doing there master's thesis in this field.
Assumed Prior Knowledge
Selection Criteria
Literature
  •  
  • Course literature will be provided by the lecturers.
Further Information
  • Part 1 in this course overlaps completely with the course Nanosafety (MAM030F, 5 hp). Part 2 of this course is a project work.
Course code
  • MAM035F
Administrative Information
  • 2022-08-29
  • Åsa Håkansson

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