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Third-Cycle Courses

Faculty of Engineering | Lund University

Details for the Course Syllabus for Course KBK031F valid from Autumn 2016

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General
Aim
  • The aim of the course is to give advanced knowledge about the technical use of enzymes and the possibilities to change and improve enzyme performance for adaptation to technical applications
Contents
  • The theoretical part of the course describes how the catalysts of the biological world, the enzymes, can be used in a variety of contexts. Examples are the use in bioanalysis, refining of food, washing powder, textile treatment and transformation of chemicals.

    The general properties of enzymes are well known from previous courses. In this course is described how enzyme molecules can be modified in order to get improved properties for technical use. Examples include genetic and chemical modification and immobilization. Immobilization, i.e. the coupling of enzymes to carrier material, is treated thoroughly. Likewise are the kinetic properties of immobilized enzymes and ways to quantify these properties emphasized.

    In the cell the enzymes function in an aqueous environment. Under certain circumstances enzymes can also work efficiently in a non-aqueous environment or in an environment with a low water activity. This opens up for unique possibilities for an enzymatic synthesis of a number of substances, including chiral substances. This kind of use of enzymes in non-conventional media is treated in great detail.

    The laboratory practical has two parts. One part where basic techniques concerning immobilization of enzymes are investigated and one research related part where untested experiments with enzymes in organic solvents are designed and carried out.
Knowledge and Understanding
  • For a passing grade the doctoral student must
  • be able to describe and evaluate methods for modifying enzymes intended for technical use
    be able to describe and evaluate methods for enzyme immobilization and for characterization of the properties of immobilized enzymes
    describe and evaluate methods for the use of enzymes in non-conventional media
    describe the technical use of enzymes
Competences and Skills
  • For a passing grade the doctoral student must
  • practically carry out enzyme immobilization, characterization of the properties of immobilized enzymes and using enzymes in organic solvents
    design, carry out and evaluate enzymatic transformations
    make written reports from laboratory practicals in which the experiments and results are described and commented upon and where deviations from expected results are analyzed and discussed
Judgement and Approach
  • For a passing grade the doctoral student must
  • in a group forum orally discuss scientific reports from the literature
    analyze, interpret and critically evaluate scientific reports related to enzyme technology
Types of Instruction
  • Lectures
  • Laboratory exercises
  • Exercises
Examination Formats
  • Written exam
  • passed reports from the laboratory practicals and passed literature discussion
  • Failed, pass
Admission Requirements
Assumed Prior Knowledge
Selection Criteria
  • Undergraduate students have priority for the practical part of the course
Literature
  • P., Danielsson, B., Larsson, P.-O., Månsson, M.-O., Ramanathan & K.: Enzyme Technology.
Further Information
  • Course coordinator: Dr Cedric Dicko, cedric.dicko@tbiokem.lth.se; Professor Patrick Adlercreutz, Patrick.Adlercreutz@biotek.lu.se

Course code
  • KBK031F
Administrative Information
  • 2017-02-09
  • Mats Ohlin

All Published Course Occasions for the Course Syllabus

3 course occasions.

Course code ▽ Course Name ▽ Division ▽ Established ▽ Course syllabus valid from ▽ Start Date ▽ End Date ▽ Published ▽
KBK031F Enzyme Technology Biotechnology 2017‑10‑18 Autumn 2016 2017‑10‑30 2018‑01‑05 2017‑10‑18
KBK031F Enzyme Technology Biotechnology Autumn 2016 2018‑11‑05 2019‑01‑19
KBK031F Enzyme Technology Biotechnology Autumn 2016 2019‑11‑05 2020‑01‑19

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