English

Every other spring semester

Proteomics is the large scale study of protein expression and function. Proteins and their modifications are often used for medical analysis of the processes involved in the progression of a disease. The methods most often used for proteomics analyses are based on mass spectrometry. An understanding of how mass spectrometers function and the processes involved is critical to understanding modern proteomics methods. We will study and discuss mass spectrometry within these criteria and discuss how one uses mass spectrometry tools to create a scientific basis for protein research.

The course is intended to give students an insight into how mass spectrometry works and can be applied to study how proteins function in a cell

In order to pass the course the students should be able to describe in detail the basic process involved in mass spectrometry and how mass spectrometry based tools can used to create a proteomic picture of proteins and how they function in a cell

In order to pass the course the students should be able to reflect in depth over mass spectrometric processes and how these methods can be used for experimental observations of protein activities

In order to pass the course the students should be able to demonstrate the ability to present, critique and debate scientific knowledge and theory within the area of mass spectrometry

Exercises

The discussion sessions will be based on PBL (the seven steps) together with problem exercises defined by the examiner, that illustrate various aspects of the theory in the course. Each of the exercises will be dealt with in two one hour meeting between the self-study periods. The course will extend over approximately 15 weeks

Oral exam

Written assignments

Active participation in the study group at a level concordant with the teaching goals. If needed, there will be written reports if the student was absent from a meeting. If the is any uncertainty about the level there will be an oral examination

Failed, pass

Accepted to a PhD or expected to be accepted

Basic knowledge of biochemistry at G-level

The course is usually run every other spring term if there are at least six students though it can be given if there are less. A maximum of ten students can be accepted per course. It will be given in English and priority will be given to students who have the course as an obligatory or alternative obligatory course in their study plan

Gross, J.: Masspektrometri - en lärobok. Tredje upplagan.. ISBN 9783319543987.

KIM020F

 -02-03

FN2/Eva Nordberg Karlsson