The course includes lectures on the following topics: strain engineering, advanced genetic tools, metabolic pathways, metabolic control analysis, metabolic flux analysis, omics and systems biology.
The literature study consists of a thorough study of research strategies on a specific topic within metabolic engineering.
In the lab simulation, the objective is to critically evaluate data arising from a set of experiments where a biofuel or bulk chemical is produced from sugars with wild-type and genetically engineered microorganisms. This includes the analysis of growth and product formation, enzyme activity and omics data,.
Exercises are performed on carbon balance, redox balance, flux analysis and metabolic control analysis.